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See, Plan, Cut: MPC-Based Autonomous Volumetric Robotic Laser Surgery with OCT Guidance

Ravi Prakash, Vincent Wang, Arpit Mishra, Devi Yuliarti, Pei Zhong, Ryan McNabb, Patrick Codd, Leila Bridgeman

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Key figure (auto-extracted from paper)
RATS achieves the first closed-loop, autonomous volumetric laser resection guided by OCT, enabling precise, obstacle-aware tissue removal with sub-millimeter accuracy.
Robotic surgery Optical coherence tomography Model predictive control Laser ablation Volumetric resection Closed-loop control

Problem

Current robotic laser surgery systems lack integrated volumetric sensing, precise imaging-to-laser calibration, and constraint-aware planning, forcing reliance on open-loop or simulation-only methods that fail in complex 3D surgical environments.

Approach

The authors developed RATS, an OCT-guided robotic platform that integrates high-resolution imaging with a fiber-coupled laser, using a super-Gaussian laser-tissue interaction model and a sampling-based model predictive control framework to generate closed-loop, constraint-aware resection trajectories.

Key results

  • Achieved 0.161 mm OCT-to-laser calibration accuracy
  • Super-Gaussian LTI model outperforms Gaussian baselines with 0.231 mm RMSE
  • MPC planner reduces resection error to 0.842 mm and improves IoU by 64.8% over feedforward execution
  • First demonstration of closed-loop autonomous volumetric laser resection with subsurface structure preservation

Why it matters

Enables precise, obstacle-aware soft tissue removal with direct clinical potential for neurosurgery and complex tumor resections.

Abstract

Robotic laser systems enable sub-millimeter, non- contact tissue resection, yet existing platforms lack volumet- ric planning and intraoperative feedback. We present RATS (Robot-Assisted Tissue Surgery), an intelligent optical co- herence tomography (OCT)-guided robotic platform for au- tonomous volumetric soft tissue resection. RATS integrates macro-scale RGB-D imaging, micro-scale OCT, and a fiber- coupled surgical laser, calibrated through a novel multistage alignment pipeline that achieves OCT-to-laser calibration ac- curacy of 0.161 ± 0.031 mm. A super-Gaussian laser–tissue interaction (LTI) model characterizes ablation morphology with an average RMSE of 0.231 ± 0.121 mm, outperform- ing Gaussian baselines. A sampling-based model predictive control (MPC) framework operates directly on OCT voxel data to generate closed-loop, constraint-aware resection trajec- tories, achieving 0.842 mm RMSE (root-mean-square error) and improving intersection-over-union agreement by 64.8% compared to feedforward execution. RATS also detects and preserves subsurface structures, demonstrating the first closed- loop autonomous volumetric robotic laser resection with OCT guidance. To our knowledge, this is the first demonstration of closed-loop autonomous volumetric robotic laser resection with OCT guidance, enabling precise, obstacle-aware tissue removal with potential in neurosurgery.

Index terms

Medical Robots and Systems Surgical Robotics: Planning Hardware-Software Integration in Robotics

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